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Wednesday, March 12, 2008

Decode Your Biological Messages To Reduce Weight

The appetite suppressants could be resorted to regulate digestive processes.

It seems at the end of the day, there is no such thing as a magic potion to reduce that bulge or tyres of yours unless you learn to decode the biological messages transmitted by your body day in day out. Read through this carefully and you may have a solution just right under your nose.

Literally speaking it is about your nose. As you walk past the serving pans of McDonalds at their outlets anywhere in the world, you cannot resist the whiff of those steaming, mouth-watering pizzas. The soft, mouth- melting burgers too are too difficult to overcome.

Mind you, all this transports you to an artificial world of aromas and flavours. For, the natural does not smell so good. Nature demands that food be hard enough for you to chew on and not swallow and gulp. While your teeth grind the food not only do the blood capillaries present in you gums are bringing fresh supply of blood at a greater rate (which keeps your teeth in good shape), your food too is undergoing the carbohydrate metabolism, a must in the chain of various metabolic processes that follow in your stomach and intestines.

The most important part of digestive activity in your mouth is that longer the food stays in the mouth, slower does it move towards the stomach, thus satiating hunger pangs in the due process with smaller quantities of food. This will not be the case if a taste-enhanced food stuff is chewed least and swallowed and allowed to enter without carbohydrate metabolism having taken place.

While in the stomach proteins are broken down into amino acids for their absorption. Fats are broken down into fatty acids for easy absorption of food elements. A stream of incompletely digested carbohydrate food particles interfere with the digestion of other types of food particles. The result is partially undigested food which lies in your bowels while the body is hungry for more. Thats when you top up the undigested morsels with fresh supply of food. Hence excessive intake of calories is unavoidable. The weight gain for most of us thus is easy. Regulate your digestive processes with intelligent and responsible eating.

Meanwhile cheap phentermine can help. Buy phentermine online. The appetite suppressant could be resorted to for regulation purposes.

Kim Parker is an associate editor to the website http://www.hateweight.com. It is committed to provide visitors with complete information on weight loss, diet pills, obesity and phentermine. We also provide articles on health related topics.

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Structure and Function of Human Skin

Human skin is a uniquely engineered organ that permits terrestrial life by regulating heat and water loss from the body whilst preventing the ingress of noxious chemicals or microorganisms. It is also the largest organ of the human body, providing around 10% of the body mass of an average person, and it covers an average area of 1.7 m2. Whilst such a large and easily accessible organ apparently offers ideal and multiple sites to administer therapeutic agents for both local and systemic actions, human skin is a highly efficient self-repairing barrier designed to keep the insides in and the outside out.

Human skin is a highly complex organ though in many transdermal drug delivery studies it is often regarded somewhat simplistically as merely a physical barrier. In vivo, skin is in a process of continual regeneration, it has immunological and histological responses to assault (as would be the case if an exogenous chemical, such as a drug, were applied to the surface) and is metabolically active. Due to experimental and ethical difficulties, most transdermal drug delivery studies tend to utilise skin ex vivo (in vitro) which inherently reduces some of the above complexity regeneration stops, immune responses cease and metabolic activity is usually lost in these studies. However, it should always be borne in mind that data obtained from excised skin may not translate directly to the in-vivo situation.

For the purpose of transdermal drug delivery, we can examine the structure and function of human skin categorised into four main layers :

the innermost subcutaneous fat layer (hypodermis)
the overlying dermis
the viable epidermis
the outermost layer of the tissue (a non-viable epidermal layer) the stratum corneum.

The subcutaneous fat layer

The subcutaneous fat layer, or hypodermis, bridges between the overlying dermis and the underlying body constituents. In most areas of the body this layer is relatively thick, typically in the order of several millimetres. However, there are areas of the body in which the subcutaneous fat layer is absent, such as the eyelids. This layer of adipose tissue principally serves to insulate the body and to provide mechanical protection against physical shock. The subcutaneous fatty layer can also provide a readily available supply of high-energy molecules, whilst the principal blood vessels and nerves are carried to the skin in this layer.

The dermis

The dermis (or corium) is typically 35 mm thick and is the major component of human skin. It is composed of a network of connective tissue, predominantly collagen fibrils providing support and elastic tissue providing flexibility, embedded in a mucopolysaccharide gel (Wilkes et al.,1973). In terms of transdermal drug delivery, this layer is often viewed as essentially gelled water, and thus provides a minimal barrier to the delivery of most polar drugs, although the dermal barrier may be significant when delivering highly lipophilic molecules. The dermis has numerous structures embedded within it; blood and lymphatic vessels, nerve endings, pilosebaceous units (hair follicles and sebaceous glands), and sweat glands (eccrine and apocrine).

The epidermis

The epidermis is itself a complex multiply layered membrane, yet varies in thickness from around 0.06 mm on the eyelids to around 0.8 mm on the load-bearing palms and soles of the feet. The epidermis contains no blood vessels and hence nutrients and waste products must diffuse across the dermo-epidermal layer in order to maintain tissue integrity.

Likewise, molecules permeating across the epidermis must cross the dermo-epidermal layer in order to be cleared into the systemic circulation. The epidermis contains four histologically distinct layers which,from the inside to the outside, are the stratum germinativum, stratum spinosum, stratum granulosum and the stratum corneum.

A fifth layer, the stratum lucidum, is sometimes described but is more usually considered to be the lower layers of the stratum corneum. The stratum corneum, comprising anucleate (dead) cells, provides the main barrier to transdermal delivery of drugs and hence is often treated as a separate membrane by workers within the field. The term viable epidermis is often used to describe the underlying layers, although the viability of cells within, for example, the stratum granulosum is questionable as the cell components degrade during differentiation.

Epidermal enzyme systems

As well as the cellular component of the epidermis, the tissue contains many drug-metabolising enzymes. Histochemical and immunohistochemical methodologies suggest that the majority of these are localised in the epidermis, sebaceous glands and hair follicles. Although present at relatively small quantities in comparison to the liver, they do allow metabolic activity that can effectively reduce the bioavailability of topically applied medicaments; a common misconception is that the skin is an inert tissue. Indeed, most phase 1 (e.g. oxidation, reduction, hydrolysis) and phase 2 (e.g. methylation, glucuronidation) reactions can occur within the skin, though these tend to be at http://www.skin-disorders.info

John Eminescu - I am a 27 years old writer and I work for a local newspaper.

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A Natural Gout Home Remedy: The Simple Gout Prevention Diet

Did you know that gout is more serious than its symptoms? Heat, pain, redness, stiffness, swelling on affected area, arthritis symptoms, and loss of sleep are all symptoms of gout.

However, did you know that gout can be a life-threatening disease if left untreated? Gout can also cause the 'silent killer' disease of high blood pressure and the painful disease of kidney stones. Simply baring the agony should NEVER be an option for gout. Your life could be at stake!

Fortunately, you can treat gout naturally without even making a $100 trip to the hospital. How? A great starting point is to change your diet with some simple tips to keep you gout free!

A Simple Gout Prevention Diet

1. Mooo! You need to immediately starting consuming more LOW-FAT dairy products.

2. Purines are BAD! Avoid foods with high purines (When purines break down in body they form uric acid which causes gout.) Typical high purine foods include: red meats, kidneys, liver, tripe and tongue. Fish have also been linked to causing gout!

3. Don't eat those veggies! What? Well, some vegetable are high in purines (uric acid) and therefore should not be touched: beans, lentils, asparagus, mushrooms, spinach and peas.

4. Water is better than Alcohol! Again, What? You should try to drink at least 10-12 glasses of water a day and watch the alcohol consumption. If you do decide to drink alcohol, no more than one drink a night!

5. Pass the Fruit! Fruits are high in Vitamin C which is great to prevent gout! You might also want to consider 'gout-fighting' Vitamin C supplements!

6. Cut some calories! Did you know that Americans generally eat twice the amount that is needed during a typical day? Look around you and see how overweight we have become and more prone to gout. Cutting 50 calories a meal will add up to around 15-20 pounds a year! So switch to diet soda, watch the condiments, easy on the chocolate, and you know the rest! With time, gout symptoms will become less and less.

7. Go for a walk! Being overweight can lead to higher levels of uric acid in your blood (cause of gout). Go for a walk each night or join a fitness club. Start out slow and have fun!

8. Weight Train! It is easier than you think! If you join a health club, you will see how easy it is to learn how to lift some weights. Simply, look at the posters on the wall and give it a try! Everybody had to learn sometime or another so do not be embarrassed! Besides, if you choose to lift some weights, you will most likely burn more calories than walking/running because of the body repairing your muscles throughout the whole day! A hard body is a gout-free body!

But Wait, There's More

Congratulations! You have just saved yourself $100 and have learned how to begin treating gout yourself! In fact, gout is a disease that you can control naturally by simply choosing the right foods, exercising, and even choosing the right herbs/fruits/food when a gout attack arises! That is right! There is a natural gout remedy for gout attacks that works in minutes. Learn about more gout prevention tips on our Cure Your Gout Website and see how thousands of people have saved hundreds of dollars and treated their gout!

http://www.cureyourgout.com/g1

Joe Barton writes for Barton Publishing Inc., a natural health company specializing in educating people of safe, affordable natural remedies. To see how you can naturally treat your gout in minutes guaranteed!

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